Neurocognitive Functions and Behavior in Joubert Syndrome

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Neurocognitive Functions and Behavior in Joubert Syndrome

Investigators from multiple Italian pediatric neurology and neurogenetics departments studied cognitive functions, behavior, and adaptive functioning in large cohort of 54 patients with Joubert syndrome (JS) as part of a prospective, multi-center study.

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Speech difficulties in Joubert syndrome

Introduction: "Joubert syndrome" was first introduced in1969. This syndrome is a rare genetic disease with autosomal dominantpattern. Hypotonia, ataxia and motor delay of the disease known as clinical manifestations. In the few reports of this syndrome, mostly functional and structural components studied and radiographic images such as speech and language developmental delay symptoms has been l...

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Joubert syndrome.

Joubert syndrome is an autosomal recessive condition in which there is a variable combination of central nervous system defects with a distinctive congenital retinal dystrophy, ocular motor abnormalities, and respiratory abnormalities in early infancy. The retinal dystrophy has been previously classified as a variant of Leber's congenital amaurosis. We report electrophysiologic and eye movement...

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MRI in Joubert Syndrome

The patient was an 8-month-old boy who was the product of a full-term and uncomplicated pregnancy. He had a remarkable family history with the presence of the same clinical course in a cousin, who was not clearly diagnosed as having Joubert Syndrome. He had apnea episodes, truncal ataxia, pendular nystagmus and mentalmotor developmental delay. He had a normal vestibuloocular reflex based on hea...

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Joubert Syndrome and related disorders

Joubert syndrome (JS) is a rare autosomal recessive condition characterized by a peculiar midbrain-hindbrain malformation, known as the molar tooth sign (MTS). The neurological presentation of JS includes hypotonia that evolves into ataxia, developmental delay, abnormal eye movements, and neonatal breathing abnormalities. This picture is often associated with variable multiorgan involvement, ma...

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 2016

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-30-12-3